Basrah Journal of Veterinary Research

HISTOLOGICAL STUDY OF THE EFFECT OF AQUEOUS EXTRACTION OF THE CASTOR SEEDS ON THE INTERNAL ORGANS IN MALE WHITE MICE

Authors

Israa S. Salman
Ahmed Q. Al-Awadi
Noor N. Jasim
Intisar A. Hassan
https://doi.org/10.33762/bvetr.2016.124254
Abstract
Water extract of castor bean was prepared and injected in mice in order to study the effect of acute phase of toxicity (in different doses) on living tissue, for these reasons, 24 male white mice were divided equally into 4 groups. The 1st, 2nd, and 3rd groups were injected with the aqueous extraction of the castor seeds subcutaneously with 20, 30 and 60 mg/Kg of body weight, respectively, while the 4th group used as control group.
After 24 hrs. the internal organs showed degenerative changes and proteintious material in the spleen and kidney, also these organs in addition to liver and stomach showed inflammatory reaction in their parenchyma. The lesions in the examined internal organs were mild in a dose of 20 mg/Kg B.W. and more sever lesions seen in a dose of 60 mg/kg of body weight.

Keywords

Castor seeds
Spleen
Lesions

Article Title العربیة

دراسة نسيجية لمعرفة تاثير المستخلص المائي لبذور الخروع على الاعضاء الداخلية للفئران البيضاء

Basrah Journal of Veterinary Research
Volume 15, Issue 1
Spring 2016
Page 54-65

  • Receive Date 01 June 2016
  • Revise Date 20 June 2016
  • Accept Date 25 June 2016
  • Publish Date 28 June 2016

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