Basrah Journal of Veterinary Research

ACTIVATION OF BACTERIAL CYTOCHROME P450 IN THE INTESTINE OF LARVAL MOSQUITOES AN INDICATION OF ITS ROLE IN THE INSECTICIDE RESISTANCE

Author

Ali Hassan Daghir Janabi
https://doi.org/10.33762/bvetr.2017.143535
Abstract
Mosquitoes apply very important impact on people life, and their control, day by day, is
getting harder and harder. This difficulty comes from different issues such as insecticide
resistance. The gut microbiome (GM) in different animals has been discovered to add principle
influence on the gastrointestinal tract physiology. For example, GM participates in degradation
of some poisonus chemicals into safer molecules that could be handled by the animal host.
Eukaryotic cytochrome P450 has been detected to inseret some degradation processes in other
animal models such as zebra fish. However, these effects are not yet known in mosquitos. In
order to stand on these problems and find if the prokaryotic P450 is involved, this study had been
done to find out if the GM has any role in developing such resistance in mosquitos. Larvae were
used in this experiment which exposed to benzothiozole (BZT) to trigger the hypothetical role of
prokaryotic P450. By using polymerase chain reaction (PCR), the result indicates that the
bacterial P450 was initiated and might be involved in the BZT exposure handling

Keywords

Bacterial cytochrome P
Mosquito gut microbiota
Benzothiazole
Basrah Journal of Veterinary Research
Volume 16, Issue 2
Autumn 2017
Page 85-91

  • Receive Date 01 December 2017
  • Revise Date 20 December 2017
  • Accept Date 25 December 2017
  • Publish Date 28 December 2017

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