The study was included 90 local cows from Al-Rashidea area which locates in the east of
Baghdad city, distributed into three groups, the smallest aged group (30) cows (1.5-2 ) years,
middle aged group (30) cows (5.5-7) years and the older aged group (30) cows (11-13) years to
study the effect progressing of age on some biochemical Criterias as indicators of oxidative stress.
The results revealed that the antioxidant enzymes, Glutathione -S-transferase GST was increased
significantly (p<0.05) ) in middle -aged group And lower value in the older aging , it was noticed
that arylesterase enzyme gradually decreased significantly with age progress. The non enzymatic
antioxidants such as Glutathione GSH revealed with the higher great value in the middle age
group and the lower significant value in the aging compared with other groups. on the other hand
Malondialdehyde (MDA) and peroxy nitrite(ONOO-) level gradually increased with progressing
of age, these events because of an increasing in production of free radicals and oxidative stress
accompanied with processing of age due to antioxidants depletion, which consider as a defense
line of body against the free radicals effects. It was concluded from this study that with aging
processes have harm effects on blood components diagnosed by reducing in antioxidants levels
and increasing of Malondialdehyde and peroxy nitrite which consider as an indicators of
oxidative stress and this support the theory of free radicals and oxidative stress and their role in
aging processes . Study the effect of aging on some biochemical parameters and antioxidant in
cow