Document Type : Research Paper
Author
Abstract
The aim of this study was to evaluate the regenerative activity of
autotransplantation of superficial flexor digital tendon and bone marrow
on the repair of sciatic nerve in dogs. Eight adult dogs from both sexes
were used. The age ranges from 1-2 years and weight from 10-15 kgs.
The animals were divided into two groups control and treatment group
each group consists of four animals. Each animal in the first group was
anesthetized with mixture of xylazine and ketamine at a dose of 5 mg/kg
and 10 mg/kg of body weight I.M, respectively. The skin of the lateral
surface of the thigh region was incised, fascia and muscle group were
separated using blunt dissection, the left sciatic nerve was harvested and a
10 mm piece was transected. A segment longer than 10 mm of superficial
flexor digital tendon was harvested and autografted using 5/0 nylon. In
the second group animals underwent the same manner of first group as
well as bone marrow applied at operative site. 60 days post operatively
results exhibited improvement in activity of affected limb in treated
animals with graft and bone marrow. Histologically there was an
improvement at site of graft represented by formation of granulation
tissue in both groups. In conclusion the local application of bone marrow on the site of tendon graft led to enhance the regeneration of sciatic nerve
resulting in functional improvement of the affected limb
Keywords
Article Title [العربیة]
تجدد العصب الورکی باستخدام الزرع الذاتی للوتر ونخاع العظم فی الکلاب
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