Author
Abstract
Open wounds have lost the barrier that protects tissues from bacterial invasion and allow
for the escape of vital fluids. The purpose of this study is to evaluate the enhancing of
therapeutic effect of Low Level Laser (LLL) and chitosan on the acceleration of open
wound healing. Forty two adult rabbits were used. They divided into three equal groups (I,
II and III). Wound was produced at the dorsal region by remove all thickness of skin at
width of 3.5cm and of length 4 cm. Group I was left without treatment, while chitosan
powder and laser therapy were used in group II and III respectively. Results of two groups
were compared with control group. Histpathologicl results at the period of 3, 7, 14, 21 and
28 days post operation reflected the presence of large number of fibroblast with formation
of new blood vessels, also the collagen fiber become dense and regular in 14 days post
operation in irradiated groups. In 21days there was formation of new and normal epidermal
closed the rupture area of III group.
Keywords
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