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This study was undertaken to find the phytochemical composition of Typha domingensis pers. Fruite and the effect of the methanolic extract on some biochemical parameters such as serum glucose , cholesterol , total protein , AST, ALT, and ALP enzymes in adult male rabbits after oral administration of different doses ( 500,1000,1500 mg/ Kg) daily for 30 days . Rabbits were divided into four groups 6 rabbits in each , group I animals received only 3 ml normal saline orally as control ,while groups(II ,III and IV) were orally administrated (500,1000,1500 mg/kg) of methanolic extract respectively .The result of the present study indicated that Typha domingensis pers. Fruite contains alkaloids, phenols, flavonoids, tannins and saponins,. Significantly decreased (p< 0.05) was observed in serum level of glucose, AST, ALT and ALP while, no significant different (p>0.05) in serum level of cholesterol and total proteins were observed as compared with control group. This study concluded that methanolic extract of Typha domingensis pers. Fruite can act as anti-diabetic and hepatoprotective agent .INTRODUCTIONThe Typha
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