Authors
Abstract
The efficacy of oil extract of the seeds of Loranthus europeus on wound healing was
investigated. After the preparation of the oil extract, the oil ointment of L. europeus was
prepared. A preliminary biochemical analysis were carried out to find out the chemical
contents of L. europeus oil extract. The study involved 18 male rabbits, they were divided
equally and randomly into 3 groups depending on post wounding biopsy: p(3'd,7Ih and l4‘hday
post wounding). Two full thickness cut wounds were done on the both sides of shoulder
regions( the left wound as control and the left as treated wound) of each group of animals.
The treated and control wounds were treated continuously with (0.5mg) oil ointment and
Vaseline base respectively, for 14”‘ day twice a day. All wounds were evaluate
macroscopically which included "measurement of contraction rate, daily wound contraction,
hyperemia, exudation and scab formation." and microscopically for "neutrophil, macrophage
infiltration, re-epithelization, fibroblast proliferation with collagen production and new blood
capillary formation". A
Both macroscopic and microscopic results showed the efficacy of L europeus seeds in
promoting the healing process significantly as compared with control wounds (P<0.05). The
oil extract treated wounds showed significant increase in hyperemia, exudation and scab
formation, neutrophils and macrophages infiltration, fibroblast proliferation with collagen
production and formation of new epithelium (re-epithelization), contraction rate and daily
wound contraction at 3”’ day post wounding, as compared with control wounds, but these
categories showed reduction at 7”‘ day except in macrophages, re—epithelization and
‘ fibroblast with collagen production which all showed significant increase at 7"‘ and 14"‘ days
post wounding as compared with control wounds. The preliminary chemical analysis for
oil extract showed the presence of Glycosides, Carbohydrates, Aldehydes & Ketones,
Trifrepenoides groups, protein and Polysaccharides, while Alkaloides, Flavonoides and
Saponins are absent.
Keywords
Article Title [العربیة]
المستخلص الزيتي لبذور نبات حب الدبق يشجع التئام الجروح
Author [العربیة]
- علاء الدين حسن جواد ميثاق عبد الرضا جاسم محمد ذياب
)
