Authors
Abstract
This study had been done on twenty four healthy adult local female rabbits of
_ mean body weight of 2 kgm and mean age of 5 months were randomly allocated into four
groups of six ainmals eash; all groups were fed during the period of experiment on a diet
contained 0.5 % cholesterol and 14% coconut oil. The first group was regarded as control
and received 3ml of physiological saline orally‘ for a month. The second group was
drenched ethanolic extract of Taraxacum ojficirzale (500 mg/kg/day) for one month; the
third group first subjected to cholecystoctomy (removal of gall bladder) then drenched 500
mg/kg/day ethanolic extract of T. oflicinale for month also. The fourth group was treated
with atrovastatin (0.4 mg/kg/day) for one month also. Those females were joined with
males after treatment for a week to study the effect on fertility and reproductive capacity
and on fetal growth. Blood samples were taken from all groups at the end of the treatment
to know the effect on serum cholesterol and on enzymatic activity then after killing the
animals the following organs were taken for histological study.
They are pituitary and thyroid glands; ovaries and uterin from each animal of each
. group. The following results were obtained:-
1. The ethanolic extract of Taraxacum ofiicinale caused highly significant increase
(p<0.01) in SGOT.
2. Atrovastatin caused significant increase i(p<0.05) in SGOT.
3. Drenching Tofiicinale extract didnot cause any significant change in SGOT of
cholecystoctomised female rabbits. ’
4. The ethanolic extract of Tofficinale and atorvastatin had caused significant decrease
(p<0.05) of SGPT in intact female rabbits but caused highly significant decrease
Keywords
Article Title [العربیة]
دراسة تاثير تجريع الخلاصة الكحولية لاوراق نبات الهندباء البرية وعقار الانورفاستاسين على نشاط انزيمات وكولسترول مصل الدم والكفاءة التناسلية وعلى الصفاة التركيبية لمحور النخامية -الدرقية-المبيض ورحم الارانب البالغة المزالة المرارة
Authors [العربیة]
- عبد الرزاق نعيم خضير منى حميد محمود
- نورس عبد الاله علوان حنان علي سلمان
)
