STUDYTHE EFFECT_ OF THE ANTIHYPERTENSIVE DRUG (TENORMIN) ON SOME BLOOD CHARACTERISTICS AND ON THE ACTIVITY OF ISOLATED LEUKOCYTES MEASURED BY CHEMILUMINESCENCE

Authors

Abstract
tenormin (atenolol) orally daily for more than three years. The other This study had been
done on thirty blood samples drown from thirty men between 40-60 years of age half of them
suffering from hypertension and taking 100mg fifteen men were healthy and did not taking
any drug and regarded as control. Those blood samples were subjected to study some
hematological parameters such as hemoglobin percentage and total erythrocyticr and
leukocytic counts. Also isolation of leukocytes was done from both hypertensive patient and
control and study their activity by chemiluminescence method.
v Result showed that prolonged treatment by tenormin of 100 mg orally daily resulted in
significant decrease (P < 0.0l)in total erythrocytic and leucocytic counts as well as the same
significant decrease in hemoglobin percentage as compared with controls , it also resulted in
significant inhibition of activity of isolated leukocytes as measured by chemiluminescence
technique which resulted from their weak reaction with the luminescence material
(lucigenin)mixed with it in the measuring chemiluminescence apparatus which is an indication
of reduced immunological ability of those leukocytes in addition to their decreased number.

Keywords


Article Title العربیة

دراسة تاثير المعالجة بالعقار المثبط لارتفاع ضغط الدم ((تينورمين)) في بعض الصفات الدموية وفي نشاط الكريات الدموية البيضاء المعزولة مقاسا بطريقة التالق الكيمياوي

Author العربیة

عبد الرزاق نعيم خضير
Volume 5, Issue 2
Autumn 2006
Page 57-65

  • Receive Date 01 December 2006
  • Revise Date 20 December 2006
  • Accept Date 25 December 2006
  • Publish Date 28 December 2006