Author
Abstract
Biopsy were taken from 50 patients in order to cultivate Helicobacter pylori and
blood samples to detect anemia , differential white blood eellcount and blood groups .
The results showed that anemia was found in 48% of the patients while lymphocyte
elevated in 44% of them , blood group 0 had the higher percentage ( 42% ) in those
patients among the other blood group types" . ' . _ _
INTRODUCTION -
Helicobacter pylori is a gram-negative microorganism that secretes many
substances including ammoina , mucolytic enzymes ( adhesins , catalase and urease ) and
acid secrete inhibitory proteins.(8) In addition to that it secrets toxin like vacuolating
cytotoxin A (vacA).(7). - —
Adhesin allows the organism to adhere , catalase might protect the organisum from
the immune system , urease increase the secretion of gastrin which stimulate the intestinal‘
tissues to grow faster , and so could result in increased cancer risk .Urease is reponsible for
hydrolyzing urea to NH3 and CO2, and acts as also protective by forming an alkalin
environment around the organism . The combination of NH3 ,_Co2 and inhibitory proteins
allows the bacteria to setup locallized pockets where it can neutralize even the acidity of
' blood type 0 stomachs
The genetics of the secretor and non —-secretor system interact to alter an
individuals risk for ulcer. In several studies , non—secretors of ABO substances have been
found to have significantly higher rate ofduodenal and peplic ulcer .( 8)
fl._ pylori infection increases the percentage of peripheral lymphocytes above the
upper limit of referential.values .(l0)e ' ‘
Recent evidence suggests that fl_. pylori infection could cause iron deficiency
anemia ( IDA ).(2). Adolescent femal athletes may have development of [_{_.__pylori
associated ( IDA ) which can be managed by Q pylori eradication (5 ) . H. pylori may
have a role in causing IDA in school-age children (3 )
Keywords
Article Title [العربیة]
العلاقة الممكنة بين الاصابة بجرثومة الملوية البوابية ومجاميع الدم وارتفاع مستويات الخلايا اللمفاوية المحيطية
Author [العربیة]
- زينة وحيد عطوان
)
