TOPICAL ACTIVITY OF_ Aloe vera (/Lverla ) EXTRACT ON EXCISION WOUND—HEALlNG OF SKIN IN RABBITTS:CLINICAL ANDA HISTOLOGICAL STUDY

Author

Abstract
plant /I/ac van: is a green succulent .cactus-like plant belonging to the lily family
,The.plant has a history of use in folk medicine for skin and otherdisorders. The objective of
the study presented in this report was to screen the extracts of this plant for its wound-
- healing properties based on its traditional use for wound healing. ethanolic extracts was
prepared for topical applications. The dose used was 150 mg/kg daily for 10 days, using the
excision wound model in rabbits. Carboxymethyl cellulose (1%) was used as control in . ‘
topical studies. Animals were randomized divided to treatment or control groups, . Wound
areas were measured. At the day Il',skin .tissue was excised for histological studies" .
Wound areas reduced significantly in all treatment groups compared to respective controls (P
< .001). Histology outcomes were consistent with changes in the treatment groups. No
differences were detected within the treatment groups. The study permits the conclusion that
Aloe Vera has wound—hea‘ling potential

Keywords


Article Title العربیة

فعالية مستخلص نبات الصبار في علاج الجروح الجلدية القطعية في الارانب البرية: دراسة سريرية نسيجية

Author العربیة

علاء عبد الخالق سواد
Volume 5, Issue 2
Autumn 2006
Page 160-169

  • Receive Date 01 December 2006
  • Revise Date 20 December 2006
  • Accept Date 25 December 2006
  • Publish Date 28 December 2006