THE EFFECT OF DIETARY HIGH FAT AND LOW PROTEIN ON BODY WEIGHT AND HISTOLOGICAL NATURE OF COLON IN BALB/C MICE

Authors

Abstract
The effect of three dietary regimes: - high fat ((1-If), low protein (Lp), and High. fat low protein
(HfLp) was studied on 3 groups of 21 days old Balb/c mice .A fourth group received balanced diet as
' control (C). histological pictures of large intestine (colon) was examined after 3,6,l2 weeks after
weaning time (day 0) ofexperiment .body weight was determined on weekly bases for the four groups.
Significant differences were detected amongmeans of body weights ofexperimental animals in
comparison with control group as following: - Hf>C>HfLp>LP.
— ' - Profound histological changes of colon were observed specially in the Hflp group in process of
time. Significant differences in numbers of goblet cells and thickness ofthe adventitial layer of colon
was detected, the numbers of goblet cells were reduced in LP group, while their numbers increased in
Hf group.

Keywords


Article Title العربیة

تاثير الغذاء مرتفع الدهون منخفض البروتين على وزن الجسم والطبيعة النسيجية للقولون في الفئران المختبرية

Authors العربیة

زينب راضي عبد الحسين
هديل توفيق الحديثي
ضمياء قاسم سكر
Abstract العربیة

The effect of three dietary regimes: - high fat ((1-If), low protein (Lp), and High. fat low protein(HfLp) was studied on 3 groups of 21 days old Balb/c mice .A fourth group received balanced diet as' control (C). histological pictures of large intestine (colon) was examined after 3,6,l2 weeks afterweaning time (day 0) ofexperiment .body weight was determined on weekly bases for the four groups.Significant differences were detected amongmeans of body weights ofexperimental animals incomparison with control group as following: - Hf>C>HfLp>LP.— ' - Profound histological changes of colon were observed specially in the Hflp group in process oftime. Significant differences in numbers of goblet cells and thickness ofthe adventitial layer of colonwas detected, the numbers of goblet cells were reduced in LP group, while their numbers increased inHf group.

Volume 5, Issue 1
Spring 2006
Page 92-96

  • Receive Date 01 June 2006
  • Revise Date 20 June 2006
  • Accept Date 25 June 2006
  • Publish Date 28 June 2006