THE ANTI-PROTOZOAL EFFECTS OF PRAZIQUANTEL ON GIARDIASIS IN MICE

Authors

Abstract
The chemotherapeutic effects of anti-eestodes drug praziquantel on giardiasis in
laboratory mice. Fourty mice were divided into 4 groups of 10 mice each. Group 1 was
infected; group2 was infected and treated orally by giving praziquantel at a dose of 10
mg/kg body weight as a single dose; group 3 was infected and treated orally by giving
metronidazole at a rate of 15-20 mg/kg body weight daily for 7' days; group 4 was
uninfected. Cyst excretion rate was recorded for the infected groups of mice.
The infected and praziquantel treated mice have recovered much more faster than
infected mice and treated by metronidazole. There were no side effects reported.
Praziquantel proved for the first time to be an ideal drug for the treatment of giardiasis

Keywords


Article Title العربیة

تاثير عقار البرازوكونتيل على داء الجيارديا في الفئران المختبرية

Authors العربیة

زينب حميد
ناظم كاظم مهدي
Volume 4, Issue 2
Autumn 2005
Page 39-41

  • Receive Date 01 December 2005
  • Revise Date 20 December 2005
  • Accept Date 25 December 2005
  • Publish Date 28 December 2005