HISTOPATHOLOGIC STUDY OF THE HEPATIC AND RENAL LESIONS INDUCED BY EXPERIMENTAL TOXIC DIETARY APPLICATION OF AFLATOXIN B; IN BROILER CHICKS

Authors

Abstract
The present study investigated the toxicologic histopathologie effect ofallatoxin Hi,
60 broiler chicks ol’ one-day aged devided randomly and equally into three groups. for
dietary study, using one group as untreated control, while the other groups were given
aflatoxin B. mixed with diet in concentration of 0.5 and 1.5 ppm respectively, for 30 days,
the study showed fatty degeneration of liver associated with bile duct prolilicration,
accompanied by infiltration of monenuclcar cells and lymphocytes. Also there was
degeneration in proximal convoluted tubules mostly as hyaline degeneration especially at
0.5 ppm dose level. Those at 1.5 ppm dose level, there was focal liver cell necrosis
associated with fibrosis and enlarged proliferated bile ducts. sever vacuolation and necrosis
of epithelial of renal proximal convoluted tubules with thickening of the glomerular
basement membrane

Keywords


Article Title العربیة

دراسة مرضیة نسیجیة للافات الکبدیة والکلویة الناجمة عن التسمم یذیفان الافلاتوکسینB فی افراخ اللحم

Author العربیة

انعام بدر فالح
Volume 4, Issue 2
Autumn 2005
Page 42-48

  • Receive Date 01 December 2005
  • Revise Date 20 December 2005
  • Accept Date 25 December 2005
  • Publish Date 28 December 2005