PATHOLOGICAL EFFECT OF TOXOCARA CANIS EGG DOSES IN EXPERIMENTAL MICE.

Authors

Abstract
In this study we examined the effect of various sensitizing doses of infective Toxocara canis eggs and the trapping of larvae in different tissues of the murine host. The level of trapping increased with sensitization egg doses. Different doses of Toxocara canis eggs were given to ten groups each with five mice and then necropsied after different periods. Experimental toxocariasis in mice sacrificed at (1,2 and 3) weeks post infection showed no lesions in mice given 50, 75 and 100 Toxocara canis eggs respectively. Other groups given higher doses of T.canis eggs between (125-500 eggs) showed lesions in liver, lungs, eyes and muscles of sacrificed mice after 4 weeks of infection.

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Article Title العربیة

التاثير المرضي لمختلف جرع بيوض الديدان السهمية في الفئران المختبرية

Volume 10, Issue 1
Spring 2011
Page 25-35

  • Receive Date 01 June 2011
  • Revise Date 20 June 2011
  • Accept Date 25 June 2011
  • Publish Date 28 June 2011