Basrah Journal of Veterinary Research

EFFECT OF VITAMIN C AND ZINC ON SOME BIOCHEMICAL PARAMETER IN ALLOXAN INDUCED DIABETIC RABBITS

Author

Zainab A. H. Al-Mousawi
https://doi.org/10.33762/bvetr.2013.76190
Abstract
Diabetes mellitus (DM) a disease which is characterized by hyperglycemia, lipoprotein abnormalities and oxidative stress. This study was undertaken to investigate the beneficial effect of vitamin C and Zinc on some biochemical parameter when induced diabetic in rabbits by alloxan. Male rabbits groups divided into four groups: Group I (Negative control) received normal saline orally, alloxan diabetic rabbits : Group II (Positive control) received normal saline orally , while Group III were orally administered 50 mg/kg body weight of vitamin C and group IV were orally administered 100 mg/kg body weight Zinc for 15 days. The results showed that vitamin C administration and zinc significantly (P< 0.05) reduced the serum glucose, total cholesterol, triglyceride, ALT and AST concentration, while there were significant changes (p< 0.05) was observed on the serum levels of total protein, albumin, globulin and albumin/ globulin ratio in diabetic group treated with vitamin C, Zinc respectively.

Keywords

diabetes mellitus
Rabbits
Alloxan

Article Title العربیة

تأثير فيتامين سي والزنك على بعض المعايير الكيموحيوية في الأرانب المصابة بداء السكري المستحدث بالالوكسان

Author العربیة

زينب عباس حسن الموسوي
Basrah Journal of Veterinary Research
Volume 12, Issue 1
Spring 2013
Page 77-86

  • Receive Date 01 June 2013
  • Revise Date 20 June 2013
  • Accept Date 25 June 2013
  • Publish Date 28 June 2013

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