ANTICOAGULANT EFFECTS OF EMINIUM SPICULATUM AQUEOUS LEAF EXTRACT IN RABBITS

Author

Abstract
The effect of different doses of Eminium spiculatum aqueous leaf extract on coagulation of blood in the rabbits were studied .Animals treated with extract at a dose of 200 , and 400 mg / kg body weight intraperitoneally daily for 7 days produced a significant ( p < 0.05 ) increase in the clotting time , prothrombin time and activated partial thromboplastin time with normal platelet counts when compared with phosphate buffer saline ( untreated ) and heparin ( treated ) control rabbits. The effect of the extract on coagulation of the blood was shown to be dose – dependent . Result of this study suggest that extract shows considerable anticoagulant activity in rabbits and has potential to reduce cardiovascular morbidity and mortality.

Keywords


Article Title العربیة

التأثير المضاد للتخثر للمستخلص المائي للاوراق نبات اللاعيا في الارانب

Author العربیة

مآب ابراهيم الفرو ه جي و باسمة عبد الفتاح البدراني
Volume 12, Issue 2
Autumn 2013
Page 332-337

  • Receive Date 01 December 2013
  • Revise Date 20 December 2013
  • Accept Date 25 December 2013
  • Publish Date 28 December 2013