Authors
Abstract
The experiment was applied on /45/ healthy male of golden Syrian hamsters,
were divided into three groups as follows: Control group(C), High Fat-High Cholesterol
group(HF-HC) and Borage Oil group (BO). All groups had laboratorial diet freely
during/15/ days(first period), after that each of HF-HC and BO groups took diet
consisting of 80% laboratorial diet+ 20% fats(13.5% sheep fat+6.5% coconut oil) for /4/
weeks(second period). The treatment of BO group changed after second period and
hamsters had laboratorial diet and dosed borage oil 2g/kg of the body weight daily for
/4/ weeks(third period). The results showed a significant increase(p=0.0000) of the total
cholesterol(TC), low density lipoprotein cholesterol (LDL-C) and triglycerides(TG)
concentrations approximately(163%, 224%, 232%) respectively in each of HF-HC and
BO groups in the second period in comparison with first period. Our results showed, in
third period, a dramatic significant decrease(P=0.0000) in the TC, LDL-C and TG
concentrations approximately (56%, 69%, 40%) respectively in BO group in comparison
with the same group of second period
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