Basrah Journal of Veterinary Research

BORAGE OIL RICH IN GAMMA LINOLENIC ACID (GLA) REDUCES CARDIOVASCULAR DISEASE (CVD) RISK FACTORS IN HAMSTERS FED IN DIET RICH IN SATURATED FATTY ACIDS (SFAS) AND CHOLESTEROL.

Authors

Ahmad Mufeed Supuh
Najeh Hapra
Mohammad Khalil Alhilal
https://doi.org/10.33762/bvetr.2014.98794
Abstract
The experiment was applied on /45/ healthy male of golden Syrian hamsters,
were divided into three groups as follows: Control group(C), High Fat-High Cholesterol
group(HF-HC) and Borage Oil group (BO). All groups had laboratorial diet freely
during/15/ days(first period), after that each of HF-HC and BO groups took diet
consisting of 80% laboratorial diet+ 20% fats(13.5% sheep fat+6.5% coconut oil) for /4/
weeks(second period). The treatment of BO group changed after second period and
hamsters had laboratorial diet and dosed borage oil 2g/kg of the body weight daily for
/4/ weeks(third period). The results showed a significant increase(p=0.0000) of the total
cholesterol(TC), low density lipoprotein cholesterol (LDL-C) and triglycerides(TG)
concentrations approximately(163%, 224%, 232%) respectively in each of HF-HC and
BO groups in the second period in comparison with first period. Our results showed, in
third period, a dramatic significant decrease(P=0.0000) in the TC, LDL-C and TG
concentrations approximately (56%, 69%, 40%) respectively in BO group in comparison
with the same group of second period

Keywords

Hamster
Borage oil
TC LDL
Basrah Journal of Veterinary Research
Volume 13, Issue 2
Autumn 2014
Page 54-65

  • Receive Date 01 December 2014
  • Revise Date 20 December 2014
  • Accept Date 25 December 2014
  • Publish Date 28 December 2014

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